Photochromic compounds can be switched back and forth by two photons of different frequency. Here, the Kottke group established a new technique (two-color step-scan) for photochromic compounds to investigate the red light sensor phytochrome, a bistable switch common in nature. Time-resolved infrared spectroscopy revealed the sequence of events in the switching mechanism. Supported by molecular dynamics simulations, the structure of the key intermediate Lumi-R is presented.
J. Ihalainen, E. Gustavsson, L. Schroeder, S. Donnini, H. Lehtivuori, L. Isaksson, C. Thöing, V. Modi, O. Berntsson, B. Stucki-Buchli, A. Liukkonen, H. Häkkänen, E. Kalenius, S. Westenhoff, and T. Kottke, J. Am. Chem. Soc. 140 (2018), 12396–12404
Aziz-Lange, Ghadwal, Glaser, Godt, Hellweg, Hoge, Kohse-Höinghaus, Kühnle, Mitzel
Life Science Chemistry
Dierks, Fischer v. Mollard, Gröger, Hellweg, Kottke, Lübke, Niemann, Sewald
Gas Phase- und Atmospheric Chemistry
Brockhinke, Eisfeld, Kohse-Höinghaus, Koop, Manthe, Mitzel
Public Understanding of Science
Dunker, Kohse-Höinghaus, Lück, Mitzel
Important subjects in the research area Molecule-based Materials are molecular magnets, biomimetic catalysts, cytostatic compounds, fluorinated compounds, organometallic compounds, silanes, spin probes an models for EPR-spectroscopy, microgels and microemulsions.
Protein crystallography is used and sulfatases, lysosomal hydrolases and membrane transport are studied in the research area Life Science Chemistry. An additional focus are bioorganic and biocatalytic topics in organic chemistry groups, which are also investigated by biochemistry groups within the Faculty of Chemistry.
Research topics in Gas Phase- und Atmospheric Chemistry are combustion, atmospheric aerosols and ice nucleation. The core facility „gas-electron diffraction and structure analysis of small molecules“ (GED@BI, N. Mitzel) is funded by the DFG and is unique within the EU.
The research area Public Understanding of Science focuses on research concerning instructions in chemistry during early childhood.
The Faculty of Chemistry is characterized by interdisciplinary research, which is typical for Bielefeld University. Researchers in the research area Molecule-based Materials cooperate with the department of Physics.
The research area Life Science Chemistry is strengthened by cooperation with the Faculty of Biology, the Faculty of Technology and the CeBiTec.
The „Center for Molecular Materials“ CM2 is an academic department with groups from chemistry and physics (coordinator B.Hoge), which aims at connections between technical know-how of industrial partners and basic research at the university.
In addition, each group is involved in national and international research cooperations.