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Computational Biology

C4 Photosynthesis

Additional information

The classic review about C4 photosynthesis
C₄ photosynthesis: a unique elend of modified biochemistry, anatomy and ultrastructure

A recent review of C4 photosynthesis in the light of RNA sequencing
Understanding metabolite transport and metabolism in C₄ plants through RNA-seq

Photosynthesis in its three varieties, such as C3 photosynthesis, C4 photosynthesis and CAM, is responsible for almost the entire storage of sunlight in organic carbon compounds. C4 photosynthesis is a highly efficient and productive metabolic pathway. We use both comparative transcriptome analysis and modeling in order to determine the necessary genes and to understand their interaction with each other. Ultimately, we intend to reconstruct the metabolic pathway with the help of synthetic biology.

Current research projects

Overview

Stoichiometric modeling and evolution
Kinetic modeling
Meta-analysis at the level of transcription for ten independent evolutionary origins

Completed projects

Overview

Recent reviews

The role of photorespiration during C4 evolution [read more]
RNA-seq based analysis of C4 [read more]

Original articles

Transcriptional comparison of a C3 and a C4 species (Cleomaceae), 2011 [read more]
Identification of the pyruvate transporter used in C4 photosynthesis (Flaveria, Asteraceae, Gynandropsis gynandra, Cleomaceae), 2011 [read more]
Proteomic comparison of C3 and C4 chloroplast envelopes (maize vs pea), 2008 [read more]
Transcriptional comparison of five species (five Flaverias, Asteraceae), 2011 [read more]
Systems level analysis of metabolomics, transcriptomics and physiological data (maize), 2011 [read more]
Kinetic and stoichiometric modeling of C4 to identify the role of photorespiration during C4 evolution, 2014 [read more]
Kinetic modeling to test subtype specific effects of C4 photosynthesis, 2014 [read more]
Transcriptional comparison of all three subtypes of C4 photosynthesis, 2014 [read more]
Network analysis along leaf development in C3 and C4 species, 2014 [read more]
PEPC enzyme choice during C4 and CAM evolution, 2014 [read more]

Please see "Publications" for any additional links

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