© Universität Bielefeld
EIC / FET
DeLIVERY
Mit zunehmendem Alter nehmen viele Menschen Medikamente für unterschiedliche Erkrankungen ein, z.B. Blutverdünner, Schmerzmittel, oder Antidepressiva. Wie sich diese Medikamente gegenseitig beeinflussen und welche Auswirkungen dies auf die Leber hat untersuchen Physiker der Universität Bielefeld und Mediziner des Universitätsklinikums OWL gemeinsam mit mehreren europäischen Partnern im Rahmen des Projekts "DeLivery". Der European Innovation Council fördert die Arbeit mit einem Pathfinder Open Grant.
Partner
- EXTREME-IR
Titel: Extreme Optical Nonlinearities in 2D materials for Far-Infrared Photonics
Projektleitung:
Prof. Dr. Dmitry Turchinovich
Fakultät für Physik
Zusammenfassung:
Generating light across the mid-infrared and terahertz regions of the spectrum has opened up a plethora of sensing applications and enabled the study of fundamental light-matter interactions. Quantum cascade lasers, which have recently moved from laboratory curiosity to industrial mainstay, have largely increased the range of practical applications. Despite their potential, they are limited in their ability to fill the far-infrared gap, namely the frequency region between 5 and 12 THz. The EXTREME-IR project aims to overcome this barrier by pioneering a radically new platform that exploits nonlinear optics in 2D materials to realise compact and coherent far-infrared sources.
Laufzeit: 09.2021-02.2025
- cassaFLOW
Titel: Cascades for Stereoselective Synthesis of Amino Acids
Projektleitung:
TU Delft
Zusammenfassung:
Non-natural amino acids are essential building blocks for pharmaceuticals. The COVID-19 drug Paxlovid is a prime example for this. But as for most pharmaceuticals, the synthesis of these amino acids is complex and requires many steps. This is especially true for amino acids with 2 stereocenters, the focus of this application. Of the group of the 20 most common natural amino acids 2 have not one but two chiral centers: isoleucine and threonine. Non-natural isomers of these 2 amino acids are surprisingly difficult to make and commercially not available via an economically viable process. At the same time they are highly important for the production of drugs like Paxlovid.
Laufzeit: 01.2024-12.2026