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  • Medizinische Fakul­tät OWL

    Medizinisches Modell eines Torso, neben dem eine Person in OP-Kleidung steht. Die Person hält das aus dem Modell entnommene Herz in der Hand.

Publikationen

Ausgewählte Veröffentlichungen

Gött-Zink L, Baum E, Kottke T (2023)
Time-resolved infrared difference spectroscopy in cells: Response of the basic region leucine zipper of aureochrome
Frontiers in Physics 11: 1150671.

Karsten L, Gött-Zink L, Schmitz J, Hoffrogge R, Grünberger A, Kottke T, Müller K (2022)
Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization Rates
Biosensors 12(5):271.

Gött-Zink L, Klocke J, Kottke T (2021)
Resolving Structural Changes of Photoreceptors in Living Escherichia coli via In-cell Infrared Difference Spectroscopy
Bio-protocol 11(3):e3909.

Gött-Zink L, Klocke J, Bögeholz LAK, Kottke T (2020)
In-cell infrared difference spectroscopy of LOV photoreceptors reveals structural responses to light altered in living cells
J. Biol. Chem. 295(33): 11729-11741.

Klocke J, Kottke T (2020)
A quantum cascade laser setup for studying irreversible photoreactions in H2O with nanosecond resolution and microlitre consumption
Phys. Chem. Chem. Phys. 22(45): 26459-26467.

Bannister S, Böhm E, Zinn T, Hellweg T, Kottke T (2019)
Arguments for an additional long-lived intermediate in the photocycle of the full-length aureochrome 1c receptor: A time-resolved small-angle X-ray scattering study
Struct. Dyn. 6(3): 34701.

Gilzer D, Hillmann R, Gött-Zink L, Klocke J, Viefhues M, Anselmetti D, Kottke T (2019)
Biphasic Formation of 2D Nanomembranes by Photopolymerization of Diacetylene Lipids as Revealed by Infrared Difference Spectroscopy
Langmuir 35(29): 9343-9351.

Klocke J, Mangold M, Allmendinger P, Hugi A, Geiser M, Jouy P, Faist J, Kottke T (2018)
Single-Shot Sub-microsecond Mid-infrared Spectroscopy on Protein Reactions with Quantum Cascade Laser Frequency Combs
Anal. Chem. 90(17): 10494-10500.

Kottke T, Xie A, Larsen DS, Hoff WD (2018)
Photoreceptors Take Charge. Emerging Principles for Light Sensing
Annu. Rev. Biophys. 47(1): 291-313.

Schröder L, Frese M, Müller C, Sewald N, Kottke T (2018)
Photochemically Driven Biocatalysis of Halogenases for the Green Production of Chlorinated Compounds
ChemCatChem 10(15): 3336-3341.

Banerjee A, Herman E, Serif M, Maestre-Reyna M, Hepp S, Pokorny R, Kroth PG, Essen L-O, Kottke T (2016)
Allosteric communication between DNA-binding and light-responsive domains of diatom class I aureochromes
Nucleic Acids Res. 44(12): 5957-5970.

Petroutsos D, Tokutsu R, Maruyama S, Flori S, Greiner A, Magneschi L, Cusant L, Kottke T, Mittag M, Hegemann P, Finazzi G, Minagawa J. (2016)
A blue-light photoreceptor mediates the feedback regulation of photosynthesis
Nature 537(7621): 563-566.

Thöing C, Oldemeyer S, Kottke T (2015)
Microsecond Deprotonation of Aspartic Acid and Response of the α/β Subdomain Precede C-Terminal Signaling in the Blue Light Sensor Plant Cryptochrome
J. Am. Chem. Soc. 137(18): 5990-5999.

Pfeifer A, Mathes T, Lu Y, Hegemann P, Kottke T (2010)
Blue Light Induces Global and Localized Conformational Changes in the Kinase Domain of Full-Length Phototropin
Biochemistry 49(5): 1024-1032.

Berndt A, Kottke T, Breitkreuz H, Dvorsky R, Hennig S, Alexander M, Wolf E (2007)
A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome
J. Biol. Chem. 282(17): 13011-13021.

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