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  • Medical School OWL

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Publications

Attaai A, Neidert N, von Ehr A, Potru PS, Zöller T, Spittau B. Postnatal maturation of microglia is associated with alternative activation and activated TGFβ signaling. Glia. 2018 Aug;66(8):1695-1708. doi: 10.1002/glia.23332. Epub 2018 Mar 25. PMID: 29575117.

Neidert N, von Ehr A, Zöller T, Spittau B. Microglia-Specific Expression of Olfml3 Is Directly Regulated by Transforming Growth Factor β1-Induced Smad2 Signaling. Front Immunol. 2018 Jul 26;9:1728. doi: 10.3389/fimmu.2018.01728. PMID: 30093905; PMCID: PMC6070609.

Spittau B, Dokalis N, Prinz M. The Role of TGFβ Signaling in Microglia Maturation and Activation. Trends Immunol. 2020 Jul 30:S1471-4906(20)30152-6. doi: 10.1016/j.it.2020.07.003. Epub ahead of print. PMID: 32741652.

Spittau B, Rilka J, Steinfath E, Zöller T, Krieglstein K. TGFβ1 increases microglia-mediated engulfment of apoptotic cells via upregulation of the milk fat globule-EGF factor 8. Glia. 2015 Jan;63(1):142-53. doi: 10.1002/glia.22740. Epub 2014 Aug 18. PMID: 25130376.

Spittau B, Wullkopf L, Zhou X, Rilka J, Pfeifer D, Krieglstein K. Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro. Glia. 2013 Feb;61(2):287-300. doi: 10.1002/glia.22435. Epub 2012 Oct 12. PMID: 23065670.

Spittau B. Aging Microglia-Phenotypes, Functions and Implications for Age- Related Neurodegenerative Diseases. Front Aging Neurosci. 2017 Jun 14;9:194. doi: 10.3389/fnagi.2017.00194. PMID: 28659790; PMCID: PMC5469878.

von Ehr A, Attaai A, Neidert N, Potru PS, Ruß T, Zöller T, Spittau B. Inhibition of Microglial TGFβ Signaling Increases Expression of Mrc1. Front Cell Neurosci. 2020 Mar 31;14:66. doi: 10.3389/fncel.2020.00066. PMID: 32296307; PMCID: PMC7137652.

Zhou X, Spittau B. Lipopolysaccharide-Induced Microglia Activation Promotes the Survival of Midbrain Dopaminergic Neurons In Vitro. Neurotox Res. 2018 May;33(4):856-867. doi: 10.1007/s12640-017-9842-6. Epub 2017 Nov 29. PMID: 29188488.

Zhou X, Zöller T, Krieglstein K, Spittau B. TGFβ1 inhibits IFNγ-mediated microglia activation and protects mDA neurons from IFNγ-driven neurotoxicity. J Neurochem. 2015 Jul;134(1):125-34. doi: 10.1111/jnc.13111. Epub 2015 Apr 23. PMID: 25827682.

Zöller T, Attaai A, Potru PS, Ruß T, Spittau B. Aged Mouse Cortical Microglia Display an Activation Profile Suggesting Immunotolerogenic Functions. Int J Mol Sci. 2018 Mar 1;19(3):706. doi: 10.3390/ijms19030706. PMID: 29494550; PMCID: PMC5877567.

Zöller T, Schneider A, Kleimeyer C, Masuda T, Potru PS, Pfeifer D, Blank T, Prinz M, Spittau B. Silencing of TGFβ signalling in microglia results in impaired homeostasis. Nat Commun. 2018 Oct 1;9(1):4011. doi: 10.1038/s41467-018-06224-y. PMID: 30275444; PMCID: PMC6167353.


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